@article{OliverHinds02272008,
author = {Hinds, Oliver and Polimeni, Jonathan R. and Rajendran,
                  Niranjini and Balasubramanian, Mukund and Amunts,
                  Katrin and Ziles, Karl and Schwartz, Eric L. and
                  Fischl, Bruce and Triantafylou, Christina},
title = {{Locating the functional and anatomical boundaries of human
                  primary visual cortex}},
journal = {NeuroImage},
volume = {In Press},
year = {2009},
abstract = {The primary visual cortex (V1) can be delineated both
                  functionally by its topographic map of the
                  visualfield and anatomically by its distinct pattern
                  oflaminar myelinzation. Although it is
                  commonlyassumed that the specialized anatomy V1
                  exhibits tscorresponds in location with functionally definte
                  V1, demonstrating this is in human has not been
                  posssible thus far due to the difficulty of
                  determing thelocation of V1 both functionally and
                  anatomically in the same individual. In this study
                  we use MRI to measure anatomical and functional V1
                  boundaries in the same individual and demonstrate
                  closeagreement between them. Functional V1 location
                  was measured by parcellating occipital cortex of 10
                  living humans into visual cortical areas based on
                  the toipographic map of the visual field measured
                  using functional MRI. Anatomical V1 location was
                  estimate for these same subejcts using a
                  surface-based probabilistic atla derived from
                  high-resolution structural MRI of the stria of
                  Gennari in 10 intact ex-vivo human hemispheres. To
                  ensure that the atlas predciction was correct, it
                  was validated against V1 location measured using an
                  observer-independent cortical parcellation based on
                  the laminar pattern of cell density in serial brain
                  sections from 10 separat individuals. The close
                  agreement between the independend anatomical and
                  functionally derived V1 boundaries indicates that
                  the whole extent of V1 can be accurately predicted
                  based on cortical surface reconstructions computered
                  from structural MRI scans, eliminating the need for
                  functional localizers of V1. In addition, that the
                  primary cortical folds predict the location of
                  functional V1 suggests that the mechanism giving
                  rise to V1 location is tied to the development of
                  the cortical folds.},
datestr = {20090401}
}